Abstract
Canine coronavirus (CCV) UWSMN-1 was originally identified from an outbreak of fatal gastroenteritis in breeding colonies. In this report, we examined whether UWSMN-1 represents a novel divergent strain or is the result of recombination events between canine and feline coronavirus strains. Sequencing of various regions of the spike and polymerase genes confirms that UWSMN-1 is widely divergent from other CCV and feline coronavirus strains. These data raise the possibility that this strain is the first member of a novel third subtype of CCV.
MeSH terms
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Animals
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Australia
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Base Sequence
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Coronavirus Infections / veterinary*
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Coronavirus Infections / virology
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Coronavirus, Canine / classification*
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Coronavirus, Canine / genetics*
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Dog Diseases / virology*
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Dogs
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Genes, pol / genetics*
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Membrane Glycoproteins / chemistry
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Membrane Glycoproteins / genetics*
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Molecular Sequence Data
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Phylogeny
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Sequence Alignment
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Sequence Analysis, DNA
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Spike Glycoprotein, Coronavirus
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Viral Envelope Proteins / chemistry
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Viral Envelope Proteins / genetics*
Substances
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Membrane Glycoproteins
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Spike Glycoprotein, Coronavirus
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Viral Envelope Proteins
Associated data
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GENBANK/AF516906
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GENBANK/AF516907