Sphingosine 1-phosphate preserves fertility in irradiated female mice without propagating genomic damage in offspring

Nat Med. 2002 Sep;8(9):901-2. doi: 10.1038/nm0902-901.
No abstract available

Publication types

  • Letter

MeSH terms

  • Animals
  • DNA Damage / drug effects
  • DNA Damage / radiation effects
  • Erythrocytes / drug effects
  • Erythrocytes / physiology
  • Erythrocytes / radiation effects
  • Female
  • Fertility / drug effects*
  • Fertility / radiation effects*
  • Litter Size
  • Lysophospholipids*
  • Male
  • Mice
  • Mice, Inbred C57BL
  • Micronucleus Tests
  • Oocytes / drug effects
  • Oocytes / physiology
  • Oocytes / radiation effects
  • Sphingosine / analogs & derivatives*
  • Sphingosine / pharmacology*

Substances

  • Lysophospholipids
  • sphingosine 1-phosphate
  • Sphingosine