We studied 54 asymptomatic postmenopausal women to characterize normal contrast-enhanced computed tomography (CT) appearance of endometrium. Endometrium was visualized in 26 out of 54 (48.1%) women, and when seen its mean short-axis thickness was 7.5 mm. The anteroposterior thickness varied directly with uterine angulation (P<.05). Endometrial attenuation was significantly less than that of the myometrium (P<.05). Endometrial thickness (short axis) and attenuation were inversely correlated to patient age and to years after menopause (P<.05). We believe that our findings will help prevent overdiagnosis of endometrial fluid or thickening in asymptomatic women.