Abstract
A series of isoindoloquinoline derivatives was synthesized and evaluated in vitro cytotoxicity against four human cancer cell lines (HCT15, SK-OV-3, MDA-MB-468 and T-47D).
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Antineoplastic Agents / chemical synthesis*
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Antineoplastic Agents / pharmacology*
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Base Pairing / drug effects
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Chemical Phenomena
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Chemistry, Physical
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DNA / drug effects
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Drug Design
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Drug Screening Assays, Antitumor
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Humans
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Indicators and Reagents
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Indoles / chemical synthesis*
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Indoles / pharmacology*
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Intercalating Agents / chemical synthesis*
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Intercalating Agents / pharmacology*
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Magnetic Resonance Spectroscopy
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Quinolines / chemical synthesis*
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Quinolines / pharmacology*
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Spectrophotometry, Infrared
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Structure-Activity Relationship
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Tumor Cells, Cultured
Substances
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Antineoplastic Agents
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Indicators and Reagents
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Indoles
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Intercalating Agents
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Quinolines
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DNA