Improved body-outline imaging technique for localization of sentinel lymph nodes in breast surgery

J Nucl Med. 2002 Sep;43(9):1181-3.

Abstract

Many centers use techniques for localizing the sentinel lymph node (SLN) associated with a breast tumor. Protocols involve the use of an intraoperative probe and blue dye but may or may not include scintigraphy.

Methods: Three methods of body-outline imaging were investigated to aid SLN localization. Body outlines were acquired using a handheld source; a transmission image was acquired from a (57)Co-flood source; and, finally, a new method is described using a (153)Gd-line source attenuation correction for body outline.

Results: Method 1 images were of low quality, although 83% of SLNs were visualized. Body outline was unsatisfactory for surgical localization. Method 2 was unsatisfactory because of the lack of a lateral image. Method 3 enabled good presurgical visualization of the SLN (73%) and speeded surgical localization.

Conclusion: The (153)Gd-line source consistently gives optimal-quality body-outline images. This source is simple, quick, and clearly locates the SLN on multiple projections.

MeSH terms

  • Breast Neoplasms / diagnostic imaging*
  • Breast Neoplasms / pathology*
  • Breast Neoplasms / surgery
  • Cobalt Radioisotopes
  • Coloring Agents
  • Female
  • Gadolinium
  • Gamma Cameras
  • Humans
  • Intraoperative Care
  • Radioisotopes
  • Radionuclide Imaging
  • Radiopharmaceuticals
  • Sentinel Lymph Node Biopsy
  • Technetium Tc 99m Aggregated Albumin

Substances

  • Cobalt Radioisotopes
  • Coloring Agents
  • Radioisotopes
  • Radiopharmaceuticals
  • Technetium Tc 99m Aggregated Albumin
  • technetium Tc 99m nanocolloid
  • Gadolinium