Wernicke's encephalopathy presenting with upbeating nystagmus

J Clin Neurosci. 2002 Jul;9(4):476-8. doi: 10.1054/jocn.2002.1121.


The case of a 49-year-old woman with Wernicke's encephalopathy is described, in which primary position upbeating nystagmus was the chief ocular sign. Although there was no history of excessive alcohol consumption, Wernicke's encephalopathy was diagnosed on a background of anorexia nervosa. The diagnosis was supported by the patient's symptomatic and clinical recovery following thiamine therapy.

Publication types

  • Case Reports

MeSH terms

  • Anorexia Nervosa / complications
  • Diagnosis, Differential
  • Female
  • Humans
  • Middle Aged
  • Nystagmus, Pathologic / diagnosis*
  • Nystagmus, Pathologic / etiology*
  • Wernicke Encephalopathy / complications*
  • Wernicke Encephalopathy / diagnosis*