Clinical research in pediatric ophthalmology: the Pediatric Eye Disease Investigator Group

Curr Opin Ophthalmol. 2002 Oct;13(5):337-40. doi: 10.1097/00055735-200210000-00008.


The Pediatric Eye Disease Investigator Group (PEDIG) is a network of university-based and community-based pediatric eye care practitioners that is conducting multiple clinical research studies. The group has conducted the Congenital Esotropia Observational Study, which assessed the early course of esotropia in infants, and the Amblyopia Treatment Studies, a series of randomized trials, the first of which compared atropine and patching for treatment of moderate amblyopia in children 3 to <7 years old. Herein, the results of these studies are summarized, and the current and future studies of the group are described.

Publication types

  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Amblyopia / therapy*
  • Atropine / therapeutic use
  • Biomedical Research
  • Child, Preschool
  • Clinical Trials as Topic
  • Esotropia / congenital*
  • Esotropia / diagnosis*
  • Humans
  • Infant
  • Mydriatics / therapeutic use
  • Sensory Deprivation


  • Mydriatics
  • Atropine