Desmoplastic small round cell tumor: imaging findings associated with clinicopathologic features

J Comput Assist Tomogr. 2002 Jul-Aug;26(4):579-83. doi: 10.1097/00004728-200207000-00018.


Purpose: To describe imaging findings of desmoplastic small round cell tumor (DSCRT) and to clarify the relation between radiologic appearances and clinicopathologic features.

Materials and methods: CT scans and MRI examinations of four male patients with histologically confirmed DSCRT (mean age = 20 years) were retrospectively analyzed.

Results: The common imaging finding was multiple peritoneal masses with regular contour situated within mesentery. Tumors showed central low attenuation in 75% of patients on nonenhanced CT. All tumors showed inhomogeneous enhancement on CT. Small foci of punctate calcification were identified in a part of the tumor in all patients. Bone metastases were identified on enhanced CT in two patients 2 and 8 months after diagnosis, respectively. Pleural dissemination was identified in all patients, and one patient had double-sided dissemination. T2-weighted MRI showed inhomogeneous high signal intensity, and small cysts were identified in two patients. Fluid-fluid levels were identified in six tumors on T2-weighted images, which suggested the presence of hemorrhage. Tumors had inhomogeneous signal intensity low or isointense relative to skeletal muscle on T1-weighted images. Two lesions exhibited inhomogeneous enhancement with central low intensity consistent with necrosis.

Conclusion: Imaging studies can depict disseminated characteristics and disease extent during the clinical course of DSRCT.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Carcinoma, Small Cell / diagnosis*
  • Carcinoma, Small Cell / pathology
  • Humans
  • Image Enhancement
  • Lymph Nodes / pathology
  • Lymphatic Metastasis
  • Magnetic Resonance Imaging*
  • Male
  • Mesentery / pathology
  • Peritoneal Neoplasms / diagnosis*
  • Peritoneal Neoplasms / pathology
  • Peritoneum / pathology
  • Tomography, X-Ray Computed*