Regulation of endothelial cell contacts during leukocyte extravasation

Curr Opin Cell Biol. 2002 Oct;14(5):587-93. doi: 10.1016/s0955-0674(02)00372-1.


The molecular mechanisms that control the opening and formation of endothelial cell contacts are of central importance for leukocyte extravasation, endothelial permeability and angiogenesis. Progress has been made in identifying novel membrane proteins at endothelial cell contacts as well as novel mechanisms that control interendothelial adhesiveness and transendothelial migration of leukocytes.

Publication types

  • Review

MeSH terms

  • Animals
  • Antigens, CD
  • Cadherins / metabolism
  • Cell Adhesion
  • Cell Communication
  • Cell Division
  • Cell Movement
  • Endothelium / cytology*
  • Humans
  • Leukocytes / cytology*
  • Neovascularization, Physiologic
  • Tight Junctions


  • Antigens, CD
  • Cadherins
  • cadherin 5