Urinary Excretion of Pneumococcal Cell Wall Polysaccharide in Children

Pediatr Infect Dis J. 2002 Aug;21(8):791-3. doi: 10.1097/00006454-200208000-00020.


The urinary excretion of the cell wall polysaccharide of Streptococcus pneumoniae was studied in 92 children with the NOW test. Cell wall polysaccharide was detected in 65% of pneumococcal carriers and in 10% of noncarriers. Excretion rates were similar in healthy children and in children with acute otitis media. The high rate of antigen excretion among nonill carriers suggests that colonization is a major source of urinary antigen in children.

MeSH terms

  • Acute Disease
  • Carrier State / microbiology
  • Carrier State / urine*
  • Child
  • Child, Preschool
  • Female
  • Health
  • Humans
  • Male
  • Otitis Media / urine
  • Polysaccharides, Bacterial / urine*
  • Streptococcal Infections / urine*
  • Streptococcus pneumoniae / chemistry
  • Streptococcus pneumoniae / isolation & purification


  • Polysaccharides, Bacterial
  • cell wall polysaccharide, Streptococcus