Green, catalytic oxidations of alcohols

Acc Chem Res. 2002 Sep;35(9):774-81. doi: 10.1021/ar010075n.


Three methods are described, in the context of the guiding principles of green chemistry, for the catalytic oxidation of alcohols. The first employs a recyclable oligomeric TEMPO catalyst (PIPO) and sodium hypochlorite as the oxidant in a bromide-free and chlorinated hydrocarbon solvent-free system. The second involves a ruthenium/TEMPO catalyst and oxygen as the oxidant. The third consists of a recyclable water-soluble palladium-diamine complex in conjunction with air as the oxidant in an aqueous biphasic system. The mechanisms of the ruthenium/TEMPO- and palladium-catalyzed oxidations are discussed, and the mechanism of the former is compared with that of the analogous copper/TEMPO catalyst.

Publication types

  • Review

MeSH terms

  • Alcohols / chemistry*
  • Catalysis
  • Chemical Industry / methods*
  • Chemical Industry / standards
  • Copper / chemistry
  • Cyclic N-Oxides / chemistry*
  • Environmental Pollution / prevention & control*
  • Industrial Waste / prevention & control
  • Oxidants / chemistry*
  • Oxygen / chemistry*
  • Palladium / chemistry
  • Ruthenium / chemistry


  • Alcohols
  • Cyclic N-Oxides
  • Industrial Waste
  • Oxidants
  • Palladium
  • Copper
  • Ruthenium
  • Oxygen