In anticipation of the need for nurses to have a strong base of knowledge and skill relative to cancer prevention and cancer control, academic institutions across the profession are being strongly encouraged by oncology nurse leaders to intensify their efforts to integrate didactic, laboratory and clinical experiences that address cancer prevention and control within nursing curricula. However, minimal attention is given to cancer prevention, risk reduction and screening in most nursing education, training, and professional development programs. The same is true relative to the incorporation of discussions, activities and experiences in clinical settings that facilitate an understanding of issues specific to cancer prevention and control racially/ethnically diverse, in high-risk, and medically underserved population groups. In an attempt to address this gap in nursing education, a Cancer Prevention and Early Detection Program for Nurse Educators was developed. Funded by a grant by the National Institutes of Health National Cancer Institute, the program aimed to provide nurse educators with state-of-the-science information and resources relative to the prevention and control of cancers in African-Americans. This report provides a summary of the programs aims, objectives, impact and outcomes.