[New aspect of local chemical contraception. Clinical study of a quaternary ammonium salt carried out by ten gynecologists and general practitioners]

Arch Med Ouest. 1975 Sep;7(7):419-21.
[Article in French]


PIP: Benzalkonium chloride was used by 10 doctors on 245 patients as a vaginal contraceptive agent. All patients were married, with a total of 190 children and 172 abortions, with a median age of 28.6. They were followed for about 19 months during which there were only 4 unplanned pregnancies, i.e. a Pearl index of 1.76, lower than contraception with IUD or with vaginal diaphragm, and comparable to hormonal contraception. 68 patients presented a case of exocervicitis, and 133 cases of leukorrhea; both problems were cured by the antiseptic action of the cream. This method proved itself very efficient, innocuous, and of excellent tolerability.

Publication types

  • English Abstract

MeSH terms

  • Age Factors*
  • Birth Rate
  • Contraception
  • Demography
  • Family Planning Services
  • Fertility
  • Marital Status*
  • Marriage
  • Parity*
  • Patient Acceptance of Health Care
  • Population
  • Population Characteristics
  • Population Dynamics
  • Pregnancy*
  • Reproductive Control Agents
  • Research*
  • Sexual Behavior
  • Spermatocidal Agents
  • Vaginal Creams, Foams, and Jellies*


  • Reproductive Control Agents
  • Spermatocidal Agents
  • Vaginal Creams, Foams, and Jellies