The Swedish Twin Registry: a unique resource for clinical, epidemiological and genetic studies

J Intern Med. 2002 Sep;252(3):184-205. doi: 10.1046/j.1365-2796.2002.01032.x.


The Swedish Twin Registry (STR), which today has developed into a unique resource, was first established in the late 1950s to study the importance of smoking and alcohol consumption on cancer and cardiovascular diseases whilst controlling for genetic propensity to disease. Since that time, the Registry has been expanded and updated on several occasions, and the focus has similarly broadened to most common complex diseases. In the following, we will summarize the content of the database, describe for the first time recent data collection efforts and review some of the principal findings that have come from the Registry.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Cohort Studies
  • Coronary Disease / epidemiology
  • Coronary Disease / genetics
  • Diseases in Twins* / epidemiology
  • Diseases in Twins* / genetics
  • Epidemiologic Methods*
  • Female
  • Genetic Predisposition to Disease*
  • Humans
  • Hypersensitivity / epidemiology
  • Hypersensitivity / genetics
  • Male
  • Mental Disorders / epidemiology
  • Mental Disorders / genetics
  • Neoplasms / epidemiology
  • Neoplasms / genetics
  • Registries*
  • Risk Factors
  • Substance-Related Disorders / epidemiology
  • Substance-Related Disorders / genetics
  • Sweden / epidemiology
  • Twin Studies as Topic / methods*