Trapping of benzene oxide-oxepin and methyl-substituted derivatives with 4-phenyl- and 4-pentafluorophenyl-1,2,4-triazoline-3,5-dione

Alistair P Henderson; Esra Mutlu; Amélie Leclercq; Christine Bleasdale; William Clegg; Richard A Henderson; Bernard T Golding

doi:10.1039/b205079j

Trapping of benzene oxide-oxepin and methyl-substituted derivatives with 4-phenyl- and 4-pentafluorophenyl-1,2,4-triazoline-3,5-dione

Chem Commun (Camb). 2002 Sep 7:(17):1956-7. doi: 10.1039/b205079j.

Authors

Alistair P Henderson¹, Esra Mutlu, Amélie Leclercq, Christine Bleasdale, William Clegg, Richard A Henderson, Bernard T Golding

Affiliation

¹ Department of Chemistry, Bedson Building, University of Newcastle upon Tyne, Newcastle upon Tyne, UK NEI 7RU.

PMID: 12271692
DOI: 10.1039/b205079j

Abstract

4-Phenyl-1,2,4-triazoline-3,5-dione and its pentafluoro analogue are efficient reagents for trapping arene oxides, e.g. benzene oxide-oxepin, affording crystalline adducts that can be quantitatively analysed by HPLC and MS techniques.