PIP: 354 women were administered megestrol acetate and ethinylestradiol as oral contraceptives for 2980 cycles (48 months). 179 women (group A) took .1 mg megestrol acetate and .1 mg ethinylestradiol, and 175 women (group B) took .5 mg megestrol acetate and .1 mg ethinylestradiol. The pregnancy rate was 2 per 100 women years with 17% lost to follow-up. Side effects included nausea, vomiting, menorrhagia, giddiness, and a white discharge. Women on sequential therapy maintained an unchanged amount of menstrual blood flow, important to Indian women.