Trigeminal nerve involvement in T-cell acute lymphoblastic leukemia: value of MR imaging

Eur J Radiol. 2002 Oct;44(1):16-8. doi: 10.1016/s0720-048x(01)00388-6.


A 30-year-old male with T-cell acute lymphoblastic leukemia presented with facial numbness. Neurological examination revealed paresthesia of the left trigeminal nerve. Cerebrospinal fluid (CSF) cytology showed no atypical cells. Gadolinium-enhanced magnetic resonance (MR) imaging demonstrated enlargement and enhancement of intracranial portions of the left trigeminal nerve. The abnormal MR imaging findings almost completely resolved after the chemotherapy. Gadolinium-enhanced MR imaging is not only a useful procedure for the early diagnosis of cranial nerve invasion by leukemia but it might be helpful to follow the changes after the treatment.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Contrast Media
  • Gadolinium DTPA
  • Humans
  • Leukemia-Lymphoma, Adult T-Cell / complications
  • Leukemia-Lymphoma, Adult T-Cell / pathology*
  • Leukemic Infiltration / diagnosis*
  • Magnetic Resonance Imaging*
  • Male
  • Trigeminal Nerve / pathology*


  • Contrast Media
  • Gadolinium DTPA