Clinical manifestations of laryngopharyngeal reflux

Ear Nose Throat J. 2002 Sep;81(9 Suppl 2):19-23.


Laryngopharyngeal reflux (LPR) is ubiquitous and associated with many head and neck symptoms and diagnoses. In some cases, the symptom is the diagnosis--for example, LPR can cause sore throat, chronic cough, globus pharyngeus, and laryngospasm. Alternately, LPR can be associated with specific histopathologic lesions--for example, vocal process granulomas. LPR can be the sole cause or an etiologic cofactor in the development of many disorders of the aerodigestive tract.

Publication types

  • Review

MeSH terms

  • Diagnosis, Differential
  • Gastroesophageal Reflux / complications*
  • Gastroesophageal Reflux / diagnosis
  • Humans
  • Laryngeal Diseases / complications*
  • Laryngeal Diseases / diagnosis
  • Pharyngeal Diseases / complications*
  • Pharyngeal Diseases / diagnosis