Translational regulations as specific traits of chloroplast gene expression

FEBS Lett. 2002 Oct 2;529(1):39-42. doi: 10.1016/s0014-5793(02)03260-x.


Studies of protein synthesis in the chloroplast compartment have revealed a unique combination of translational autoregulations and trans-regulations due to the delivery of a variety of nuclear factors that act post-transcriptionally. We show how these two characteristics concur to set the major step in the regulation of chloroplast gene expression at the translational level, leading to a surprisingly low sensitivity of chloroplast protein synthesis in response to extensive changes in plastome copy number and transcript concentration.

Publication types

  • Review

MeSH terms

  • Animals
  • Chlamydomonas reinhardtii / genetics
  • Chloroplasts / genetics*
  • Chloroplasts / metabolism
  • Cytochromes / genetics
  • Cytochromes / metabolism
  • Cytochromes f
  • Gene Expression Regulation*
  • Homeostasis
  • Protein Biosynthesis*


  • Cytochromes
  • Cytochromes f