Pulmonary alveolar microlithiasis in childhood: clinical and radiological follow-up

Pediatr Pulmonol. 2002 Nov;34(5):384-7. doi: 10.1002/ppul.10183.


This report describes a case of pulmonary alveolar microlithiasis that was diagnosed in an 8.5-year-old girl by high-resolution computed tomography (CT) and open lung biopsy. Presence of symptoms (productive cough, fever), their periodic occurrence (lasting up to 1 week), and comparatively long asymptomatic periods should be emphasized. Despite extensive X-ray abnormalities, tests of pulmonary interstitium involvement and exercise tests revealed normal results. A therapeutic regimen, including disodium etidronate, was administered for 18 months with no significant clinical or radiological improvement.

Publication types

  • Case Reports

MeSH terms

  • Child
  • Etidronic Acid / therapeutic use
  • Female
  • Humans
  • Lithiasis / diagnostic imaging*
  • Lithiasis / drug therapy
  • Lithiasis / pathology
  • Lung Diseases, Interstitial / diagnostic imaging*
  • Lung Diseases, Interstitial / drug therapy
  • Lung Diseases, Interstitial / pathology
  • Tomography, X-Ray Computed


  • Etidronic Acid