Apnoea in a former preterm infant after caudal bupivacaine with clonidine for inguinal herniorrhaphy

Paediatr Anaesth. 2002 Sep;12(7):637-40. doi: 10.1046/j.1460-9592.2002.00924.x.

Abstract

Awake regional anaesthesia for inguinal hernia repair in former preterm infants is suggested to avoid life-threatening respiratory complications known to occur after general anaesthesia. Caudal anaesthesia is becoming a more popular technique for this purpose. To prolong duration of anaesthesia and to reduce postoperative need for analgesics in these infants, caudal clonidine has been considered useful. We report a former preterm infant, who had two awake caudal anaesthetics for herniotomy within 3 weeks. The first was uneventful with bupivacaine 0.25% at 35 weeks postconceptional age. At 38 weeks, the baby suffered form intra- and postoperative apnoeas after inadvertent administration of bupivacaine 0.125% plus clonidine.

Publication types

  • Case Reports

MeSH terms

  • Anesthesia, Caudal / adverse effects*
  • Anesthetics, Combined / administration & dosage
  • Apnea / chemically induced*
  • Bupivacaine / administration & dosage*
  • Clonidine / administration & dosage
  • Clonidine / adverse effects*
  • Hernia, Inguinal / congenital
  • Hernia, Inguinal / surgery*
  • Humans
  • Infant
  • Infant, Newborn
  • Infant, Premature
  • Intraoperative Complications / chemically induced
  • Male
  • Medication Errors*
  • Postoperative Complications / chemically induced

Substances

  • Anesthetics, Combined
  • Clonidine
  • Bupivacaine