The mammalian Golgi--complex debates

Nat Rev Mol Cell Biol. 2002 Oct;3(10):789-95. doi: 10.1038/nrm933.

Abstract

Since the first description of the Golgi in 1898, key issues regarding this organelle have remained contentious among cell biologists. Resolving these complex debates, which revolve around Golgi structure-function relationships, is prerequisite to understanding how the Golgi fulfils its role as the central organelle and sorting station of the mammalian secretory pathway.

Publication types

  • Historical Article
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Animals
  • Biological Transport, Active
  • COP-Coated Vesicles / physiology
  • COP-Coated Vesicles / ultrastructure
  • Golgi Apparatus / physiology*
  • Golgi Apparatus / ultrastructure
  • History, 19th Century
  • History, 20th Century
  • Models, Anatomic
  • Models, Biological
  • Signal Transduction