Late problems in tetralogy of Fallot--recognition, management, and prevention

Cardiol Clin. 2002 Aug;20(3):395-404. doi: 10.1016/s0733-8651(02)00010-3.


Most adults with previous repair of tetralogy of Fallot lead unrestricted lives and are asymptomatic. Residual RVOT problems such as significant PR and/or RVOT obstruction however are common and often lead to gradual RV dilation and dysfunction with consequent supraventricular or ventricular arrhythmias. Hemodynamic causes for the tachyarrhythmia should be sought and corrected, and therapy directed towards suppressing the arrhythmia (antiarrhythmics, cryoablation or AICD) should be carried out as well. Recent changes in the surgical approaches to the repair of tetralogy at the time initial repair may well translate into a reduced incidence of late complications.

Publication types

  • Review

MeSH terms

  • Adult
  • Cardiovascular Surgical Procedures / adverse effects
  • Cardiovascular Surgical Procedures / methods
  • Child, Preschool
  • Female
  • Genetic Counseling / methods
  • Heart Diseases / etiology
  • Humans
  • Male
  • Postoperative Complications*
  • Pregnancy
  • Pregnancy Complications, Cardiovascular / prevention & control*
  • Tetralogy of Fallot / complications
  • Tetralogy of Fallot / diagnosis*
  • Tetralogy of Fallot / prevention & control
  • Tetralogy of Fallot / surgery*
  • Time Factors