Mitochondria and apoptosis: new therapeutic targets

Adv Cancer Res. 2002;85:203-42. doi: 10.1016/s0065-230x(02)85007-2.
No abstract available

Publication types

  • Review

MeSH terms

  • Animals
  • Antineoplastic Agents / pharmacology*
  • Apoptosis / drug effects
  • Apoptosis / physiology*
  • BH3 Interacting Domain Death Agonist Protein
  • Biological Transport
  • Carrier Proteins / physiology
  • Drug Design
  • Glycolysis / drug effects
  • Humans
  • Intracellular Membranes / drug effects
  • Intracellular Membranes / metabolism
  • Membrane Proteins / physiology
  • Mitochondria / drug effects
  • Mitochondria / enzymology
  • Mitochondria / physiology*
  • Models, Molecular
  • Neoplasm Proteins / physiology
  • Neoplasms / drug therapy
  • Neoplasms / metabolism
  • Neoplasms / pathology
  • Neoplastic Stem Cells / cytology*
  • Neoplastic Stem Cells / drug effects
  • Oxidative Phosphorylation
  • Permeability / drug effects
  • Protein Conformation
  • Proto-Oncogene Proteins / physiology
  • Proto-Oncogene Proteins c-bcl-2 / antagonists & inhibitors
  • Proto-Oncogene Proteins c-bcl-2 / genetics
  • Proto-Oncogene Proteins c-bcl-2 / physiology
  • bcl-2 Homologous Antagonist-Killer Protein
  • bcl-2-Associated X Protein
  • bcl-X Protein

Substances

  • Antineoplastic Agents
  • BAK1 protein, human
  • BCL2L1 protein, human
  • BH3 Interacting Domain Death Agonist Protein
  • BID protein, human
  • Carrier Proteins
  • Membrane Proteins
  • Neoplasm Proteins
  • Proto-Oncogene Proteins
  • Proto-Oncogene Proteins c-bcl-2
  • bcl-2 Homologous Antagonist-Killer Protein
  • bcl-2-Associated X Protein
  • bcl-X Protein