Bilateral symmetrical frontoparietal polymicrogyria

Eur J Paediatr Neurol. 2002;6(4):229-32. doi: 10.1053/ejpn.2002.0599.


A patient with bilateral symmetrical frontoparietal polymicrogyria is reported. Severe developmental delay, mental retardation, spastic tetraplegia, and seizures were the main clinical features. Magnetic resonance imaging revealed bilateral thick cortex with irregular gyri and festoon-like grey-white matter junction in the frontoparietal areas. Bilateral frontoparietal polymicrogyria might represent either a severe form of a spectrum of malformations involving the frontoparietal area or a further variety of the congenital bilateral symmetrical polymicrogyria syndromes in addition to bilateral frontal polymicrogyria, bilateral perisylvian syndrome, and bilateral parasagittal parieto-occipital polymicrogyria.

Publication types

  • Case Reports

MeSH terms

  • Child
  • Electroencephalography
  • Frontal Lobe / abnormalities*
  • Frontal Lobe / physiopathology*
  • Functional Laterality / physiology*
  • Humans
  • Intellectual Disability / diagnosis
  • Magnetic Resonance Imaging
  • Male
  • Parietal Lobe / abnormalities*
  • Parietal Lobe / physiopathology*
  • Quadriplegia / diagnosis
  • Quadriplegia / physiopathology
  • Severity of Illness Index
  • Subarachnoid Space / pathology