Skip to main page content
Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
, 2 (5), 440-8

Are Islet Cells the Gatekeepers of the Pancreas?


Are Islet Cells the Gatekeepers of the Pancreas?

Parviz M Pour et al. Pancreatology.


The pancreas is one of the body's most complex tissues composed of a mixture of endocrine and exocrine cell components. Although, islets comprise 1-2% of the pancreatic volume, there is some evidence that they control the function and the integrity of the pancreas and play the role of a gatekeeper. This review intends to highlight the importance of islet cells, not only for glucose metabolism, but also for their significant role in drug metabolism and diseases, especially in pancreatic cancer.

Similar articles

See all similar articles

Cited by 4 PubMed Central articles

Publication types