Inheritance of the endoplasmic reticulum and Golgi apparatus

Curr Opin Cell Biol. 2002 Aug;14(4):496-9. doi: 10.1016/s0955-0674(02)00345-9.


Yeast and mammalian cells use a variety of different mechanisms to ensure that the endoplasmic reticulum and Golgi apparatus are inherited by both daughter cells on cell division. In yeast, endoplasmic reticulum inheritance involves both active microtubule and passive actin-based mechanisms, while the Golgi is transported into the forming daughter cell by an active actin-based mechanism. Animal cells actively partition the endoplasmic reticulum and Golgi apparatus, but association with the mitotic spindle-rather than the actin cytoskeleton-appears to be the mechanism

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Actins / metabolism
  • Animals
  • Endoplasmic Reticulum / genetics*
  • Endoplasmic Reticulum / metabolism
  • Endoplasmic Reticulum / physiology
  • Golgi Apparatus / genetics*
  • Golgi Apparatus / metabolism
  • Golgi Apparatus / physiology
  • Humans
  • Microtubules / metabolism
  • Mitosis
  • Nuclear Envelope / metabolism
  • Saccharomyces cerevisiae / genetics
  • Spindle Apparatus / physiology


  • Actins