Photodynamic therapy for circumscribed choroidal haemangioma

Acta Ophthalmol Scand. 2002 Oct;80(5):531-6. doi: 10.1034/j.1600-0420.2002.800513.x.


Purpose: To assess the efficacy of photodynamic therapy (PDT) as a new treatment for circumscribed choroidal haemangioma (CCH).

Methods: Eight patients with CCH were treated with PDT using a protocol similar to that used in the standard treatment of neovascular age-related macular degeneration.

Results: Visual acuity improved in six of eight eyes, remained unchanged in one eye and deteriorated in one eye after 3-15 months (median 7 months) follow-up. Pre-treatment metamorphopsia disappeared in all but two cases. The thickness of the CCH measured with standardized echography showed marked regression within 1 month after PDT. In six eyes there was no remaining protrusion after PDT and one lesion was barely detectable. One patient experienced a transient choroidal effusion and perifoveal haemorrhage.

Conclusion: Photodynamic therapy is a promising new treatment for CCH as it restores visual function in most cases without causing apparent ocular or systemic side-effects.

MeSH terms

  • Adult
  • Aged
  • Antineoplastic Agents / therapeutic use*
  • Choroid Neoplasms / diagnostic imaging
  • Choroid Neoplasms / drug therapy*
  • Female
  • Fluorescein Angiography
  • Hemangioma / diagnostic imaging
  • Hemangioma / drug therapy*
  • Humans
  • Male
  • Middle Aged
  • Photochemotherapy*
  • Photosensitizing Agents / therapeutic use*
  • Porphyrins / therapeutic use*
  • Ultrasonography
  • Verteporfin
  • Visual Acuity


  • Antineoplastic Agents
  • Photosensitizing Agents
  • Porphyrins
  • Verteporfin