Czech miner studies of lung cancer risk from radon

J Radiol Prot. 2002 Sep;22(3A):A107-12. doi: 10.1088/0952-4746/22/3a/319.

Abstract

Epidemiological evidence of lung cancer risk from radon is based mainly on studies of miners. Two such studies among Czech uranium miners were established in 1970 and 1980. A subcohort of 5002 miners and a nested-in case-control study contribute to a joint European project. In this paper, the subcohort of miners with 495 lung cancers is described. The excess relative risk depends linearly on cumulative exposure incurred more than 5 years before. The relative effect from exposures in the distant past decreases by 62% per decade. Simultaneously, the excess relative risk is lower by 43% per decade in dependence on age at exposure. The effect of smoking, partly analysed in the study, suggests a twofold elevation in the relative risk coefficient among non-smokers, but this difference is not significant.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Aged
  • Air Pollutants, Occupational / adverse effects*
  • Air Pollutants, Radioactive / adverse effects*
  • Case-Control Studies
  • Cohort Studies
  • Czech Republic
  • Humans
  • Lung Neoplasms / etiology*
  • Male
  • Middle Aged
  • Mining*
  • Neoplasms, Radiation-Induced / etiology*
  • Occupational Diseases / etiology*
  • Occupational Exposure
  • Radiation Dosage
  • Radon / adverse effects*
  • Risk Factors
  • Uranium*

Substances

  • Air Pollutants, Occupational
  • Air Pollutants, Radioactive
  • Uranium
  • Radon