Epidural analgesia and backache: a randomized controlled comparison with intramuscular meperidine for analgesia during labour

Br J Anaesth. 2002 Sep;89(3):466-72.

Abstract

Background: Concern has been expressed that epidural analgesia for labour may be associated with a higher incidence of backache.

Methods: A prospective randomized trial investigating the effect of epidural analgesia on the outcome of labour in nulliparae, mothers were randomized to receive either epidural analgesia or meperidine. A questionnaire on postnatal symptoms was sent to them 6 months after delivery.

Results: In all, 611 mothers were studied; 310 were randomly allocated to receive i.m. meperidine up to 300 mg and 301 to receive epidural bupivacaine. The response rate to our questionnaire was 83%. Intention-to-treat analysis showed similar prevalence rates of postpartum backache in the epidural (48%) and meperidine groups (50%), with an observed difference (epidural-meperidine) of -2% (95% CI, -11 to +6%). After excluding mothers with backache before delivery, there were also similar incidence rates of postpartum backache in the epidural (29%) and meperidine groups (28%), observed difference 1% (95% CI, -8 to +10%).

Conclusions: Epidural analgesia in labour was not associated with an increase in the prevalence or incidence of backache.

Publication types

  • Clinical Trial
  • Comparative Study
  • Randomized Controlled Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Analgesia, Epidural / adverse effects*
  • Analgesia, Obstetrical / adverse effects*
  • Analgesia, Obstetrical / methods
  • Analgesics, Opioid*
  • Back Pain / etiology*
  • Back Pain / prevention & control
  • Female
  • Humans
  • Meperidine*
  • Obstetric Labor Complications / etiology*
  • Obstetric Labor Complications / prevention & control
  • Pain Measurement
  • Pregnancy
  • Prospective Studies
  • Puerperal Disorders / etiology
  • Surveys and Questionnaires

Substances

  • Analgesics, Opioid
  • Meperidine