Phase II enzyme-inducing and antioxidant activities of beetroot (Beta vulgaris L.) extracts from phenotypes of different pigmentation

J Agric Food Chem. 2002 Nov 6;50(23):6704-9. doi: 10.1021/jf020575a.

Abstract

Free-radical scavenging, reducing, and phase II enzyme-inducing activities of aqueous and 5% aqueous ethanol extracts of freeze-dried root tissue of four beet (Beta vulgaris L.) strains (red, white, orange, and high-pigment (red) phenotypes) were determined. Aqueous and ethanolic tissue extracts of the regular and high-pigment red phenotypes were most capable of inhibiting metmyoglobin/H(2)O(2)-mediated oxidation of 2-2'-azino-bis(3-ethylbenzthiazoline-6-sulfonic acid) (ABTS) and 2,2'-azobis-(2-amidinopropane) dihydrochloride (AAPH)-mediated bleaching of beta-carotene. These same extracts were also most efficient at reducing ABTS radical cation and inducing quinone reductase in murine hepatoma (Hepa 1c1c7) cells in vitro.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Amidines / chemistry
  • Animals
  • Antioxidants / analysis*
  • Antioxidants / pharmacology
  • Benzothiazoles
  • Beta vulgaris / chemistry*
  • Enzyme Induction / drug effects*
  • Ethanol
  • Free Radicals / chemistry
  • Hydrogen Peroxide / chemistry
  • Liver Neoplasms, Experimental
  • Metmyoglobin / chemistry
  • Mice
  • NAD(P)H Dehydrogenase (Quinone) / biosynthesis
  • Phenotype
  • Pigments, Biological / analysis*
  • Plant Extracts / chemistry*
  • Plant Extracts / pharmacology
  • Sulfonic Acids / chemistry
  • Tumor Cells, Cultured
  • Water
  • beta Carotene / chemistry

Substances

  • Amidines
  • Antioxidants
  • Benzothiazoles
  • Free Radicals
  • Pigments, Biological
  • Plant Extracts
  • Sulfonic Acids
  • beta Carotene
  • Water
  • Metmyoglobin
  • 2,2'-azino-di-(3-ethylbenzothiazoline)-6-sulfonic acid
  • Ethanol
  • 2,2'-azobis(2-amidinopropane)
  • Hydrogen Peroxide
  • NAD(P)H Dehydrogenase (Quinone)