Cytogenetics and molecular genetics of bladder cancer: a personal view

Am J Med Genet. 2002 Oct 30;115(3):173-82. doi: 10.1002/ajmg.10693.

Abstract

The cytogenetic and molecular genetic aspects that may be involved in the pathogenesis of bladder cancer are presented. Although anomalies of chromosome 9 may play an initial causative role in this cancer, the subsequent events, involving a succession of genetic changes, are less established or understood. This presentation is a distillation of what generally are considered to be the cytogenetic and molecular genetic events that constitute the array of changes underlying bladder cancer.

Publication types

  • Review

MeSH terms

  • Chromosome Aberrations
  • Chromosomes, Human, Pair 9
  • Humans
  • Urinary Bladder Neoplasms / etiology
  • Urinary Bladder Neoplasms / genetics*