Abstract
When a nascent vesicle buds, the membrane must curve. Several mechanisms have been proposed for curvature creation or stabilization. Structural analysis of the ENTH domain of the endocytic protein epsin has suggested a new mechanism, in which the ENTH domain pushes its way into membranes, thus bending them into shape.
MeSH terms
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Adaptor Proteins, Vesicular Transport
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Animals
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Carrier Proteins / chemistry
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Carrier Proteins / physiology*
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Cell Membrane / physiology*
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Cell Size
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Endocytosis*
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Models, Biological
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Models, Molecular
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Neuropeptides / chemistry
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Neuropeptides / physiology*
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Protein Structure, Tertiary / physiology
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Vesicular Transport Proteins*
Substances
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Adaptor Proteins, Vesicular Transport
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Carrier Proteins
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Neuropeptides
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Vesicular Transport Proteins
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epsin