Cohort mortality study of German cockpit crew, 1960-1997

Epidemiology. 2002 Nov;13(6):693-9. doi: 10.1097/01.EDE.0000029605.69271.8E.


Background: Cockpit crew in civil aviation are exposed to several potential health hazards, among them cosmic ionizing radiation. To assess the influence of occupational and other factors on mortality we conducted a cohort study among cockpit crew.

Methods: All pilots and other cockpit personnel of two German airlines were traced through registries and other sources for the period 1960-1997. Standardized mortality ratios, with German population rates as the reference, were calculated. We estimated the individual radiation dose based on individual job histories and assessed dose-response trends in stratified and regression analyses.

Results: We compiled a cohort of 6061 male cockpit personnel, yielding 105,037 person-years of observation. The maximum estimated individual radiation dose was 80.5 mSv. Among 255 deaths overall (standardized mortality ratio [SMR] = 0.48; 95% confidence interval [CI] = 0.42-0.54) there were 76 cancer deaths (SMR = 0.56; CI = 0.43 - 0.74). Most cancer and cardiovascular SMRs were reduced. A slight increase was seen for brain cancer (SMR = 1.68; CI = 0.66-3.62). Employment duration was associated with the all-cancer mortality in Poisson regression analyses. No other dose-response relation was found.

Conclusions: German cockpit crew have a low overall and cancer mortality. The role of occupational causes, and particularly cosmic radiation, appears limited.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aerospace Medicine
  • Aviation*
  • Cause of Death
  • Cohort Studies
  • Cosmic Radiation / adverse effects
  • Germany / epidemiology
  • Humans
  • Male
  • Mortality / trends*
  • Neoplasms / epidemiology
  • Neoplasms / mortality
  • Retrospective Studies
  • Survival Rate
  • Time Factors