Intrarenal neuroblastoma diagnosed by fine-needle aspiration: a report of two cases

Diagn Cytopathol. 2002 Nov;27(5):294-7. doi: 10.1002/dc.10184.


Neuroblastoma is an infrequent tumor of childhood usually located at any site containing sympathetic neural tissue-retroperitoneum and adrenal gland being the most common locations, followed by thoracopulmonary region, mediastinum, head and neck, and pelvis. Two primary renal neuroblastomas were diagnosed in a 6-yr-old boy and a 7-mo-old boy by computed tomography (CT)-guided fine-needle aspiration (FNA) cytology. The smears contained numerous individually scattered small and round cells, with scanty cytoplasm, related to a fibrillary matrix. Scattered larger cells with slightly more cytoplasm were seen among the smaller ones. No tubular or glomeruloid differentiation was noted. Considering the age and cytomorphology, a diagnosis of intrarenal neuroblastoma was made in both cases. An intrarenal mass in a child may occasionally be a neuroblastoma. Our cases demonstrate the usefulness of CT-guided FNA in diagnosing intrarenal masses in children.

Publication types

  • Case Reports

MeSH terms

  • Biopsy, Needle
  • Brain Neoplasms / pathology
  • Brain Neoplasms / secondary
  • Child
  • Diagnosis, Differential
  • Fatal Outcome
  • Humans
  • Infant
  • Kidney Neoplasms / diagnostic imaging
  • Kidney Neoplasms / pathology*
  • Lung Neoplasms / secondary
  • Male
  • Neuroblastoma / diagnostic imaging
  • Neuroblastoma / pathology*
  • Tomography, X-Ray Computed
  • Wilms Tumor / pathology