Global replacement of tryptophan with aminotryptophans generates non-invasive protein-based optical pH sensors

Angew Chem Int Ed Engl. 2002 Nov 4;41(21):4066-9. doi: 10.1002/1521-3773(20021104)41:21<4066::AID-ANIE4066>3.0.CO;2-6.
No abstract available

MeSH terms

  • Amino Acid Sequence
  • Bacterial Proteins / chemistry
  • Base Sequence
  • Biosensing Techniques / instrumentation
  • Biosensing Techniques / methods*
  • Fluorescence
  • Hydrogen-Ion Concentration
  • Models, Molecular
  • Optics and Photonics
  • Protein Conformation
  • Protein Engineering*
  • Proteins / chemical synthesis
  • Proteins / chemistry*
  • Spectrophotometry, Ultraviolet
  • Tryptophan / analogs & derivatives*
  • Tryptophan / chemical synthesis
  • Tryptophan / chemistry*

Substances

  • Bacterial Proteins
  • Proteins
  • barstar protein, Bacillus amyloliquefaciens
  • Tryptophan