Aspergillus nidulans is frequently resistant to amphotericin B

Mycoses. 2002 Nov;45(9-10):406-7. doi: 10.1046/j.1439-0507.2002.00797.x.


The high failure rate of amphotericin B-based therapy in patients with Aspergillus nidulans infections may not be entirely a result of host factors as suggested previously. Innate resistance of A. nidulans to polyenes may contribute to the poor response in patients.

Publication types

  • Letter

MeSH terms

  • Amphotericin B / pharmacology*
  • Amphotericin B / therapeutic use
  • Antifungal Agents / pharmacology*
  • Antifungal Agents / therapeutic use
  • Aspergillosis / drug therapy
  • Aspergillosis / microbiology
  • Aspergillus nidulans / drug effects*
  • Aspergillus nidulans / isolation & purification
  • Drug Resistance, Microbial*
  • Humans
  • Microbial Sensitivity Tests
  • Treatment Outcome


  • Antifungal Agents
  • Amphotericin B