Abstract
The reductive opening of epoxyimonobactams 1 with titanoncene (III) chloride gives rise to radicals that can be trapped by intramolecular pi systems (i.e., conjugated alkenes and lactone and amide carbonyls) in a stereospecific way to give new carbocyclic compounds such as tribactam 2.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Epoxy Compounds / chemistry
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Free Radicals
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Heterocyclic Compounds, 3-Ring / chemical synthesis*
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Organometallic Compounds
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Stereoisomerism
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beta-Lactams / chemical synthesis*
Substances
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Epoxy Compounds
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Free Radicals
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Heterocyclic Compounds, 3-Ring
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Organometallic Compounds
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beta-Lactams
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titanocene dichloride