Ultraviolet light C in the treatment of chronic wounds with MRSA: a case study

Ostomy Wound Manage. 2002 Nov;48(11):52-60.


The prevalence of antibiotic-resistant bacteria such as methicillin-resistant Staphylococcus aureus is rapidly increasing in healthcare facilities and spreading to the community. Methicillin-resistant S. aureus colonize the skin and open wounds and can interfere with wound healing. Recent studies have shown that ultraviolet light C can kill antibiotic-resistant strains of bacteria such as methicillin-resistant S. aureus in both laboratory cultures and animal tissue. This clinical report describes the effects of ultraviolet light C on wound bioburden and closure in three people with chronic ulcers infected with methicillin-resistant S. aureus. In all three patients, ultraviolet light C treatment reduced wound bioburden and facilitated wound healing. Two patients had complete wound closure following 1 week of ultraviolet light C treatment. This case study suggests that ultraviolet light C is a promising adjunctive therapy for chronic wounds containing antibiotic-resistant bacteria such as methicillin-resistant S. aureus.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Aged, 80 and over
  • Chronic Disease
  • Female
  • Humans
  • Male
  • Methicillin Resistance / radiation effects*
  • Skin Ulcer / microbiology*
  • Skin Ulcer / radiotherapy*
  • Staphylococcus aureus / isolation & purification*
  • Staphylococcus aureus / radiation effects*
  • Ultraviolet Therapy*