Neuropsychological outcome in children with acquired or congenital renal disease

Pediatr Nephrol. 2002 Nov;17(11):908-12. doi: 10.1007/s00467-002-0912-4. Epub 2002 Sep 25.


The neuropsychological abilities of children with congenital ( n=13) or acquired ( n=11) end-stage renal disease (ESRD) were compared. Patients were being treated with or being prepared for dialysis and were awaiting transplantation. None of the children had an identifiable syndrome with associated central nervous system (CNS) dysfunction or had exposure to drugs with known CNS toxicity. There were no group differences in intelligence, academic achievement, behavior, or immediate memory. Children with congenital ESRD had poorer fine motor coordination and more difficulty on tests of verbal and nonverbal long-term memory than children with acquired ESRD. However, the neuropsychological outcome for congenital ESRD is more favorable than previously described. Psychological and education treatment recommendations should be considered.

Publication types

  • Clinical Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Age of Onset
  • Behavior
  • Child
  • Educational Status
  • Female
  • Humans
  • Intelligence Tests
  • Kidney Diseases / congenital*
  • Kidney Diseases / psychology*
  • Kidney Diseases / therapy
  • Kidney Failure, Chronic / congenital
  • Kidney Failure, Chronic / psychology
  • Kidney Failure, Chronic / therapy
  • Male
  • Memory / physiology
  • Neuropsychological Tests*
  • Peritoneal Dialysis
  • Renal Dialysis
  • Treatment Outcome