Towards a molecular characterization of adaptation in local populations

Curr Opin Genet Dev. 2002 Dec;12(6):683-7. doi: 10.1016/s0959-437x(02)00349-0.


Adaptation of local populations to their environment is central to our understanding of biodiversity and processes of speciation; nevertheless, the genetic changes that are required for such local adaptations are understood poorly. Recent studies have shown that multilocus scans that compare different populations for several loci can identify genomic regions carrying a mutation that results in a local adaptation.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Adaptation, Biological / genetics*
  • Animals
  • Fundulidae / genetics
  • Genetic Markers
  • Genetic Variation
  • Genetics, Population
  • Isoenzymes / genetics
  • L-Lactate Dehydrogenase / genetics
  • Microsatellite Repeats
  • Polymorphism, Genetic


  • Genetic Markers
  • Isoenzymes
  • L-Lactate Dehydrogenase
  • lactate dehydrogenase 1