Quantification of the refrigerants R22 and R134a in mixtures by means of different polymers and reflectometric interference spectroscopy

Anal Bioanal Chem. 2002 Nov;374(5):858-67. doi: 10.1007/s00216-002-1557-7. Epub 2002 Oct 8.


The aim of this study was the quantification of vapors of the ozone-depleting refrigerant R22 in the presence of its most important substitute R134a, by the use of the reflectometric interference spectroscopy and polymers as sensitive layers. First, the sorption characteristic of different types of polymers exposed to the vapors of the two analytes was investigated. Then, binary mixtures of the two refrigerants were measured with an array set-up on the basis of six polymer sensors. The measurements were evaluated by the use of neural networks, whereby low limits of detection of 0.45 percentage volume (vol. %)for R22 and 1.45 vol. % for R134a could be established. Additionally, one polar polymer and one microporous polymer were selected for the measurements with a low-cost set-up. The quantification of R22 in the presence of R134a with this low-cost set-up was possible with a limit of detection of 0.44 vol. %, which would enable a fast and economical monitoring at recycling stations.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Air Pollutants / analysis*
  • Calibration
  • Chlorofluorocarbons, Methane / analysis*
  • Equipment Design / standards
  • Hydrocarbons, Fluorinated / analysis*
  • Neural Networks, Computer
  • Polymers
  • Reproducibility of Results
  • Sensitivity and Specificity
  • Spectrum Analysis / instrumentation
  • Spectrum Analysis / methods
  • Spectrum Analysis / standards
  • Transducers


  • Air Pollutants
  • Chlorofluorocarbons, Methane
  • Hydrocarbons, Fluorinated
  • Polymers
  • fluorocarbon 22
  • norflurane