[Effect of methergine, oxytocin, pyridoxine (vitamin B 6) and quinestrol on prolactin and milk secretion in puerperium]

Arch Gynakol. 1975 Nov 18;219(1-4):469-70. doi: 10.1007/BF00669189.
[Article in German]

Abstract

PIP: Plasma prolactin levels and milk volume were studied in 50 maternity patients for 8 days after delivery. 1 group of patients received no medication, while other groups received methergine (.2 mg 3 times daily), syntocinon (200 u 3 times daily), Vitamin-B6 (300 mg twice daily), or quinestrol (4 mg, single dose), respectively. None of these influenced prolactin secretion substantially although prolactin levels were slightly higher in the quinestrol-treated group. There was no evidence of an antilactation effect of Vitamin-B6, while the lactation-inhibiting effect of Quinestrol must be ascribed to a periperal effect.

MeSH terms

  • Female
  • Humans
  • Lactation / drug effects*
  • Methylergonovine / pharmacology*
  • Norpregnatrienes / pharmacology*
  • Oxytocin / pharmacology*
  • Postpartum Period
  • Pregnancy
  • Prolactin / metabolism*
  • Pyridoxine / pharmacology*
  • Quinestrol / pharmacology*

Substances

  • Norpregnatrienes
  • Oxytocin
  • Prolactin
  • Quinestrol
  • Pyridoxine
  • Methylergonovine