Using ECG-gated multidetector CT to evaluate global left ventricular myocardial function in patients with coronary artery disease

AJR Am J Roentgenol. 2002 Dec;179(6):1545-50. doi: 10.2214/ajr.179.6.1791545.


Objective: Retrospectively ECG-gated three-dimensional volume data from multidetector CT (MDCT) coronary angiography enable image reconstruction of the cardiac cycle in the diastolic and systolic phases. The objective of our study was to investigate the feasibility of determining left ventricular function from MDCT coronary angiography data sets in 22 patients with coronary artery disease and to study the correlation of MDCT results with those of functional data from biplane cineventriculography.

Conclusion: Multiplanar reformations from three-dimensional MDCT data allowed good delineation of endocardial and epicardial left ventricular contours. In patients evaluated for coronary artery disease, MDCT coronary angiography with retrospective ECG gating provides functional data in an acceptable correlation (r = 0.8; p < 0.05) to biplane cineventriculography.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Aged
  • Cineradiography
  • Coronary Angiography*
  • Coronary Disease / diagnostic imaging*
  • Coronary Disease / physiopathology
  • Electrocardiography*
  • Feasibility Studies
  • Female
  • Humans
  • Male
  • Middle Aged
  • Prospective Studies
  • Stroke Volume
  • Tomography, X-Ray Computed* / methods
  • Ventricular Function, Left*