Peripheral nerve granuloma in a patient with tuberculosis

J Neurol Neurosurg Psychiatry. 2002 Dec;73(6):769-71. doi: 10.1136/jnnp.73.6.769.

Abstract

The cause of peripheral neuropathy associated with tuberculosis is controversial. Possibilities include an immune mediated neuropathy, direct invasion of nerves, vasculitic neuropathy, compressive neuropathy, a meningitic reaction, and the toxic effects of antituberculous chemotherapy. This report describes the unusual finding of granulomas in the peripheral nerve of a patient with tuberculosis. The pathological findings were of a delayed hypersensitivity reaction, but with no more specific indications of the mechanism of the neuropathy.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Biopsy
  • Diagnosis, Differential
  • Follow-Up Studies
  • Humans
  • Male
  • Neurologic Examination
  • Peripheral Nervous System Diseases / diagnosis*
  • Peripheral Nervous System Diseases / pathology
  • Sural Nerve* / pathology
  • Tuberculoma / diagnosis*
  • Tuberculoma / pathology
  • Tuberculosis, Lymph Node / diagnosis
  • Tuberculosis, Lymph Node / pathology