The relationship between the visually evoked P300 event-related potential and gamma band oscillation in the human medial and basal temporal lobes: an electrocorticographic study

Neurosci Res. 2002 Dec;44(4):421-7. doi: 10.1016/s0168-0102(02)00159-1.

Abstract

We have recorded electrocorticographic activities (ECoG) from subdural electrodes on the human medial temporal lobe (MTL) and basal temporal lobe (BTL) in epileptic patients during cognitive visual tasks designed to evoke the P300 event related potential (ERP). From those recordings we examined the event related gamma band oscillation (ERGBO) and P300 ERP. While P300 was predominantly observed in the MTL, ERGBO was observed in both MTL and BTL. Resembling to P300, ERGBO responses were more often observed following rare stimuli than frequent stimuli. In average responses the ERGBO to rare stimuli followed P300, beginning at 440.5 ms and continuing for about 100 ms. Past studies suggest P300 ERP component reflects a role in cognitive function. Since ERGBO in the present study appeared in different regions and at a different latency from P300, ERGBO may reflect a different physiological role in the cognitive process.

MeSH terms

  • Adult
  • Biological Clocks / physiology*
  • Cognition / physiology*
  • Electroencephalography
  • Epilepsy / physiopathology*
  • Event-Related Potentials, P300 / physiology*
  • Evoked Potentials, Visual / physiology*
  • Female
  • Humans
  • Male
  • Photic Stimulation
  • Psychomotor Performance / physiology
  • Reaction Time / physiology
  • Temporal Lobe / anatomy & histology
  • Temporal Lobe / physiology*