Screening for retinopathy of prematurity: evaluation and modification of guidelines

Br J Ophthalmol. 2002 Dec;86(12):1399-402. doi: 10.1136/bjo.86.12.1399.

Abstract

Aims: To evaluate current screening guidelines for ROP (retinopathy of prematurity) and to determine whether they can be modified.

Methods: In accordance with the authors' present criterion, infants born in Stockholm County, Sweden, from 1 August 1998 to 31 July 2000, with a gestational age of < or =32 weeks, were screened for ROP. The effectiveness of screening was studied.

Results: The incidence of ROP was 25.5% in this study. A dropout group comprising almost 20% of the population studied (< or =32 weeks), was never referred, were lost to follow up, or died before screening was completed. No infant with a gestational age of >31 weeks at birth developed severe ROP (stages 3-5) and no infant with a gestational age of >29 weeks was treated for ROP.

Conclusion: 80% of infants in this population with a gestational age at birth of < or =32 weeks, the current screening criterion, were effectively screened for ROP. The authors recommend that the screening criterion be lowered to </=31 weeks since no infant with severe ROP would have been missed.

MeSH terms

  • Birth Weight
  • Female
  • Gestational Age
  • Humans
  • Incidence
  • Infant, Newborn
  • Infant, Premature
  • Logistic Models
  • Male
  • Practice Guidelines as Topic
  • Predictive Value of Tests
  • Prospective Studies
  • Regression Analysis
  • Retinopathy of Prematurity / diagnosis*
  • Retinopathy of Prematurity / epidemiology
  • Sweden / epidemiology
  • Vision Screening / methods*