Effects of serum vitamin E levels on skin vitamin E levels in dogs and cats

Vet Ther. 2002 Fall;3(3):235-43.


Skin problems are common in small animal practice. Oxidative stress, or the imbalance between prooxidants and the body's antioxidant defense system, likely plays a role in the development of skin disease. According to this study, increasing amounts of vitamin E in foods for dogs and cats increases serum and cutaneous concentrations of vitamin E. Based on available scientific data, these increases in vitamin E concentration are likely to be beneficial. However, the relationship between increases in serum and skin vitamin E concentrations and the prevention, development, and treatment of skin disease remains to be elucidated by intervention studies.

Publication types

  • Clinical Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animal Feed
  • Animals
  • Antioxidants / analysis
  • Cats / blood*
  • Dogs / blood*
  • Female
  • Logistic Models
  • Male
  • Skin / chemistry*
  • Vitamin E / administration & dosage
  • Vitamin E / analysis*
  • Vitamin E / blood*
  • Vitamin E / pharmacology


  • Antioxidants
  • Vitamin E