Involvement of a CCAAT-binding complex in the expression of a nitrogen-starvation-specific gene, isp6+, in Schizosaccharomyces pombe

Biosci Biotechnol Biochem. 2002 Oct;66(10):2224-7. doi: 10.1271/bbb.66.2224.


The fission yeast gene isp6+ is needed in nitrogen-starvation response but its transcriptional regulation has been unclear. isp6+ was repressed under nutrient conditions, in which cAMP-dependent protein kinase A, the stress-activated protein kinase cascade, and the CCAAT-binding complex were concerned. The CCAAT-binding complex also was involved in the induction of isp6+ during nitrogen starvation.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Blotting, Northern
  • CCAAT-Binding Factor / metabolism*
  • Cyclic AMP-Dependent Protein Kinases / metabolism
  • Fungal Proteins / metabolism*
  • Membrane Proteins / metabolism*
  • Mutation / genetics
  • Nitrogen / metabolism*
  • Protein Kinases / metabolism
  • Schizosaccharomyces / genetics*
  • Schizosaccharomyces / metabolism*
  • Schizosaccharomyces pombe Proteins*
  • Transcription, Genetic


  • CCAAT-Binding Factor
  • Fungal Proteins
  • Membrane Proteins
  • Schizosaccharomyces pombe Proteins
  • isp6 protein, S pombe
  • Protein Kinases
  • Cyclic AMP-Dependent Protein Kinases
  • Nitrogen