Human exposure following Mycobacterium tuberculosis infection of multiple animal species in a Metropolitan Zoo

Emerg Infect Dis. 2002 Nov;8(11):1290-3. doi: 10.3201/eid0811.020302.

Abstract

From 1997 to 2000, Mycobacterium tuberculosis was diagnosed in two Asian elephants (Elephas maximus), three Rocky Mountain goats (Oreamnos americanus), and one black rhinoceros (Diceros bicornis) in the Los Angeles Zoo. DNA fingerprint patterns suggested recent transmission. An investigation found no active cases of tuberculosis in humans; however, tuberculin skin-test conversions in humans were associated with training elephants and attending an elephant necropsy.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Animal Husbandry
  • Animals
  • Animals, Zoo / microbiology*
  • DNA Fingerprinting
  • Disease Outbreaks
  • Female
  • Genotype
  • Humans
  • Los Angeles
  • Male
  • Mycobacterium tuberculosis / genetics
  • Mycobacterium tuberculosis / isolation & purification*
  • Polymorphism, Restriction Fragment Length
  • Risk Factors
  • Surveys and Questionnaires
  • Tuberculin Test
  • Tuberculosis / microbiology*
  • Tuberculosis / transmission*
  • Zoonoses / microbiology
  • Zoonoses / transmission*